Endocrine Abstracts

BackgroundDiabetes Insipidus is a complex and heterogeneous clinical syndrome affecting water balance, resulting in large volumes of dilute urine. Determining the mechanism and etiology of diabetes insipidus, as well as differentiating it from other pathologies that cause polyuria and polydipsia has always been a challenge since water deprivation test is not always conclusive and antidiuretic hormone can not be reliably measured in the circulation.<p...

IntroductionHypopituitarism is the partial or complete loss of anterior pituitary function that can result from acquired or congenital causes. Understanding its clinical aspects in children could lead to early diagnosis and therefore better outcome.ObjectiveThe aim of this study is to evaluate the characteristics of presentation, and etiology of Hypopituitarism in children.Methods<p...

IntroductionPsychogenic polydipsia (PPD), also known as self-induced water intoxication, is mostly seen in psychiatric populations. PPD can lead to life threatening complications and may even be lethal if not diagnosed and treated early. The aim of this study is to determine the clinical and biological features of PPD.Patients and methodsA retrospective study including 11 patients consulting for polydipsia at...

IntroductionGynecomastia is the most common breast condition in men. The aim of our study is to describe clinical and therapeutic characteristics of patients with gynecomastia.MethodsA descriptive retrospective study was conducted in the department of endocrinology at the Hedi Chaker hospital, Sfax, Tunisia.ResultsWe collected the data of 28 patients with an avera...

IntroductionDeQuervain’s subacute thyroiditis (DST) is a rare pathology, defined by the involvement of the thyroid gland by an inflammatory process probably of viral origin, not suppurative and not autoimmune. In this context, we report 4 cases of TSD followed up in the endocrinology department over a period of 23 years, to highlight diagnostic and therapeutic particularities.ResultsThe average age was 3...

IntroductionCardiothyreosis is associated with higher morbidity and mortality than other forms of hyperthyroidism. The aim of our study was to identify its therapeutic and evolutive aspects in an adult population of southern Tunisia.MethodsRetrospective study including all cases of cardiothyreosis followed in our department during a period of 20 years.Results100 c...

Introduction: Lymphangioma is a rare benign malformation of the lymphatic system that typically affects the neck and head during childhood. Adrenal glands are an uncommon and rare location for lymphangioma. Herein, we report an unusual clinical presentation of an adrenal lymphangioma revealed by Cushing syndrome.Case report: A 69-year-old female was referred to our department for exploration of an adrenal incidentaloma. Her medical history was positive f...

Introduction: Congenital hyperinsulinism (CHI) is a rare disease with an incidence of 1 in 30,000. It is the most common cause of persistent neonatal hypoglycemia, primarily due to inhibitory mutations in genes encoding the ATP-sensitive potassium channel in pancreatic beta cells, with ABCC8 (SUR1) and KCNJ11 (Kir6.2) mutations being the most frequent. In this context, we report a highly unusual case in terms of phenotypic and evolutionary aspects.Clinic...

Introduction: Mitochondrial diabetes (MD) is characterized by a wide spectrum of phenotypic and genotypic manifestations. Through a cohort study of 40 patients with MD, we attempted to establish a correlation between this diversity of phenotypic expression and the biomolecular substrate of the mitochondrial genome within the Tunisian population.Results: Epidemiologically and anthropometrically, our series aligns with literature data, with an onset age of...

Background: To be able to manage their disease and live with it, type 2 diabetic patients need to understand and be aware of their disease. Educational diagnosis should therefore assess patients’ perception of their diabetes.Aims: This study aims to carry out a self-assessment of diabetic patients’ knowledge of their diseaseMethods: Our study is a descriptive and analytical cross-sectional study which took place during th...